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Publish Date : 22-Dec-2014

Medtronic, Inc. today announced it has completed global user evaluations of a next generation system that uses the new pump platform and represents a key step toward development of an artificial pancreas. The completely redesigned insulin delivery system comes with new features that offer convenience in managing diabetes and improved design elements that make the system easy to use. Medtronic's next generation system uses the new platform along with a new Predictive Low Glucose Management (PLGM) algorithm. PLGM automatically stops insulin delivery when the sensor measures a glucose level predicted to approach the predetermined lowest limit, and then resumes insulin delivery after those glucose levels recover. Manufacturing has been initiated, and product introduction in select countries is set for early calendar year 2015. A pivotal trial is currently underway in the United States to evaluate PLGM technology as well.

"By delivering on our commitments to drive technical innovations around the world, we aim to transform diabetes care so that more people living with diabetes can enjoy greater freedom and experience better health," said Alejandro Galindo, vice president and general manager of the Intensive Insulin Management business at Medtronic. Continued advancements in technologies to manage diabetes are driving better health outcomes. The landmark STAR 3 study concluded that adults, children and adolescents can achieve better glucose control without an increase in hypoglycemia by using integrated insulin pump therapy with CGM compared to the current standard of care - multiple daily injectionsi. Improving glycemic control reduces the risk of long-term diabetes complications such as eye disease, kidney disease, nerve damage and heart disease.

The introduction of a new insulin delivery platform that offers more convenience in managing diabetes demonstrates the next step toward Medtronic's ultimate goal of developing a fully automated artificial pancreas - a system that would automatically adjust insulin levels based on sensor glucose levels with very little interaction from the patient. Previous milestones include:
2006: Medtronic introduced the world's first integrated insulin pump and continuous glucose monitor
2009: Medtronic introduced the world's first integrated insulin pump with Low Glucose Suspend technology in Europe
2013: Medtronic introduced the MiniMed 530G with Enlite, which features Threshold Suspend technology, in the U.S.
2014: Medtronic begins pivotal trial for PLGM technology in the U.S.

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