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Netherlands : CEPI awards contract worth up to US$12.5 million to develop a human vaccine against Rift Valley fever
Publish Date : 16-Jul-2019
Wageningen Bioveterinary Research (WBVR), part of Wageningen University & Research, and the Coalition for Epidemic Preparedness Innovations (CEPI) hereby announce a new partnering agreement. With support from the European Unions (EUs) Horizon 2020 programme, CEPI will provide up to US$12.5 million for vaccine manufacturing, preclinical research, and a phase 1 study to assess the safety, tolerability, and immunogenicity of a single-dose vaccine candidate (RVFV-4s) against Rift Valley fever virus for use in humans. WBVR will lead a consortium of research, manufacturing, and clinical evaluation organisations to undertake this project.
To produce this vaccine candidate, researchers at WBVR have altered the genome of the Rift Valley fever virus in a way that significantly weakens it. This attenuated virus will be used as a vaccine to generate a lasting immune response against the disease. This investment is part of CEPIs third call for proposals, launched earlier this year with support from the EUs Horizon 2020 research and innovation programme under grant agreement No. 8579341.
