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Publish Date : 04-Oct-2013

Memorial Sloan-Kettering Cancer Center, The Rockefeller University and Weill Cornell Medical College announced today that they have formed the pioneering Tri-Institutional Therapeutics Discovery Institute, Inc. (Tri-I TDI) and have partnered with Takeda Pharmaceutical Company, Ltd. This new, groundbreaking institute, designed to expedite early-stage drug discovery into innovative treatments and therapies for patients, was founded thanks to a generous $15 million gift by Lewis and Ali Sanders and a $5 million gift from Howard and Abby Milstein.

The Tri-Institutional Therapeutics Discovery Institute represents a novel partnership of academic institutions working together to more effectively develop therapeutics that arise from discoveries made in basic science labs. Its focus is on the early stages of developing compounds that make possible all-important "proof of concept" studies – those that increase the likelihood that targeting a specific biologic pathway can favorably alter the course of a disease.

Furthermore, the institute's partnership with Takeda, a global research-based pharmaceutical company with a strong record of bringing new medicines to market, will benefit drug discovery work at all three institutions.

"We are excited to help contribute to solving an important societal problem: how to improve the efficiency of drug development. The process is currently fragmented, with many wasteful steps, on top of the structural, intellectual and funding barriers that have made it so difficult to translate basic research into clinical application," said Dr. Laurie H. Glimcher, the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College. "With academia and industry working together closely, guiding each other in the laboratory, we have a better chance to translate research discoveries into lasting medical contributions and to do so with far greater efficiency. We are privileged to have Takeda, a proven leader in pharmaceutical development, join with us at this momentous occasion, as the Tri-I TDI begins its work speeding discoveries to the bedside. We thank Takeda for its forward-thinking vision, and applaud Mr. Sanders and Mr. Milstein for their commitment to drive innovation and discovery with their generous support."

"This institute will greatly enhance the ability of basic science labs at the three institutions to translate their discoveries into new medicines," said Dr. Marc Tessier-Lavigne, president of The Rockefeller University. "This exciting collaboration between academic institutions will also serve as a link between institutional researchers and industry experts in medicinal chemistry, compound screening and drug development. It's a partnership that will help lower barriers in the drug discovery process and ultimately lead to new therapies for some of our most difficult and deadly diseases."

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